Gravity causing more piston wear is BS. Its not like the piston never touchs the cylinder wall in a inline engine. In all engines the pistons rock around in the cylinder bores. Its a function of rods angles, accelerations, blah blah blah. Any engine when you take it apart has piston scuffing on the skirts. The piston rocking is what that familar noise is when you have forged pistons in the motor (which require a greater clearance and make a louder slaping sound).
The big deal with inline 6s vs V6s is the packaging. The inline 6 is a long narrow tall motor. Try and install one in a transverse engine FWD car is a pain. Imagine having a Camry that has to be 2 feet wider to fit the engine. The other problem is the length and height. Most cars today want a low hood line so a tall motor doesn't help. Many RWD cars today also try and push the engine as far back as possible for weight distribution. The big downside on a V6 is cost, you end up with many extra parts. But with most cars FWD today V6s are the choice, and because of that they get used in RWD cars as well for cost reasons. There was a time when almost all 6s were inline, but the cars were all RWD back then. I6s also have a long crank which doesn't help crank torsional rigidity.
The difference in engine vibrations from a 60 degree V6 and a inline 6 are relatively minimal. All engine vibrations are classed in terms of "order". There are 1st order, 2nd, 3rd, 4th ...... one millionth etc. Each progressive one is weaker than the next. Something like a one cylinder mower engine isn't balanced in 1st order shaking in the piston bore direction and shakes like crazy. The typical inline 4 has shaking of the 2nd order in the bore direction. 60 degree V6 have a twisting moment about the crankshaft in the 2nd order range. I6s are balanced up till the 4th or 6th order or something like that. You usually don't care beyond the 2nd or 3rd order because the shaking forces are minimal. Basically the order thing is like a funcition of crankshaft speed. 2nd order forces are cyclical at 2X crankshaft speed. This is why balance shafts in most engines run at 2X engine speed. The counterweights on the crank are designed to minimize shaking at engine speed, since the crank can only spin at engine speeds.
Engine vibration comes from the piston moving up and down in its bore (F=ma, a piston has mass and the accelleration is huge so big F) an the weight of the crank pin/big rod end moving round and round (think of spinning around with a dumbell outstretched at 6000 RPM, you'd be lucky to stand up

). Usually you can counteract these forces with equals and opposites. This is why most engines are symmetrical along the length (i.e the I4 the two center piston are at TDC the outside 2 are at BDC, this counteracts the pistons up and down force at 1x engine speed). Oh well enough rambling..... can you tell I studied this stuff way too much in college.