Could be that a valve is stuck. Could be that the injectors simply suck, fuel pressure could be too low, there could be a vacuum leak somewhere and certain cylinders are running too lean because of a bad gasket or cracked port/runner.
If it is running so bad then I would suggest you just take it apart and search for the problem rather than risking complete desctruction of something valuable.
If it is running so bad then I would suggest you just take it apart and search for the problem rather than risking complete desctruction of something valuable.